Table 1.
Sensitivity, specificity, and percent agreements of A) professional AN- versus professional NMT-sampling, and B) self NMT- versus professional NP-sampling. The results are also differentiated by high and low viral load (≥/< 7 log10 SARS-CoV2 RNA copies/ml).
| Viral load SARS-CoV2 RNA copies/ml |
Sampling method | Sensitivity n/N % (95%CI) |
Specificity n/N (%; 95%CI) |
Positive Percent Agreement % (95%CI) |
Negative Percent Agreement % (95%CI) |
|---|---|---|---|---|---|
| (A) Prof.-sampling | |||||
| All (N = 36) | Prof. AN | 31/36 86.1% (71.3–93.9) |
96/96 100.0% (95.7–100.0) |
31/31 100.0% (88.9–100.0) |
96/96 100.0 % (95.9–100.0) |
| Prof. NMT | 31/36 86.1% (71.3–93.9) |
96/96 100.0% (95.7–100.0) |
|||
| ≥7 log10 (N = 29) | Prof. AN | 28/29 96.6% (82.8–99.8) |
|||
| Prof. NMT | 28/29 96.6% (82.8–99.8) |
||||
| <7 log10 (N = 7) | Prof. AN | 3/7 42.9% (15.8–75.0) |
|||
| Prof. NMT | 3/7 42.9% (15.8–75.0) |
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| (B) Self-sampling | |||||
| All (N = 34) | Self NMT | 31/34 91.2% (77.0–97.0) |
61/62 98.4% (91.4–99.9) |
30/31 96.8% (83.8–99.8) |
63/65 96.9% (89.5–99.2) |
| Prof. NP | 31/34 91.2% (77.0–97.0) |
62/62 100% (94.2–100.0) |
|||
| ≥7 log10 (N = 25) | Self NMT | 25/25 100.0% (86.7–100.0) |
|||
| Prof. NP | 25/25 100.0% (86.7–100.0) |
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| <7 log10 (N = 9) | Self NMT | 6/9 66.7% (35.4–87.9) |
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| Prof. NP | 6/9 66.7% (35.4–87.9) |
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Prof.: professional sampling; self: self-sampling; AN: anterior nasal; NMT: nasal mid-turbinate.