Table 4. Microscopic smear results through day 28 post-CHMI.
CA (N = 16) |
CAT (N = 16) |
Infectivity Control (N = 12) |
|
---|---|---|---|
Positive Blood Smears, n (%) | 15 (94%) | 11 (69%) | 11 (92%) |
Negative Blood Smears, n (%) | 1 (6%) | 5 (31%) | 1 (8%) |
Time to 1st Positive Smear (Days) | 10.1, 10.9, 10.9, 10.9, 11.2, 11.8, 11.9, 11.9, 11.9, 12.0, 12.0, 12.5, 13.8, 13.9, 14.0 | 10.0, 10.9, 11.1, 11.8, 12.5, 13.4, 13.8, 13.9, 14.0, 14.5, 17.0 | 8.8, 9.9, 10.9, 10.9, 10.9, 11.0, 11.9, 11.9, 13.9. 13.9, 13.8 |
Mean (SD) | 11.98 (1.16) | 12.98 (1.98) | 11.62 (1.68) |
Median | 12.99 | 13.42 | 11 |
Vaccine Efficacy (VE), % (95% CI) | -2% (-26.5–17.3) | 25% (-8.8–48.3) | NA |
p-value: 0.8352 | p-value: 0.0746 | NA |
VE = (1—Relative Risk).
P-values were calculated by Cochran-Mantel-Haenszel method.
CI: Confidence Interval.