Table 2.

Physiological and EVD drainage parameters during CSF drainage challenge

	Pre-CSF drainage (mm Hg)	Post-CSF drainage (mm Hg)
MAP
BEFORE mannitol	77 ± 10	78 ± 6
AFTER mannitol	76 ± 8	75 ± 11
ICP
BEFORE mannitol	29 ± 7	23 ± 6*
AFTER mannitol	27 ± 6	16 ± 4*
CPP
BEFORE mannitol	46 ± 2	54 ± 9
AFTER mannitol	47 ± 9	60 ± 10
Volume OF CSF drained (ML)
BEFORE mannitol	4 ± 1
AFTER mannitol	6 ± 3*

CPP: cerebral perfusion pressure; CSF: cerebrospinal fluid; EVD: external ventricular drain; ICP: intracranial pressure; MAP: mean arterial pressure

*p < 0.05