| 1.1 Adherence: number of people completing treatment (12 weeks' duration) |
1 |
|
Odds Ratio (M‐H, Random, 95% CI) |
Totals not selected |
| 1.1.1 Change to pharmacotherapy |
1 |
|
Odds Ratio (M‐H, Random, 95% CI) |
Totals not selected |
| 1.2 Adherence: compliance by prescription refill (21.6–26 weeks' duration) |
2 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 1.2.1 Adherence aids |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 1.2.2 Education |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 1.3 Adherence: Adherence among Patients with Chronic Disease scale (8 weeks) |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 1.4 Adherence % (change to pharmacotherapy) (12 weeks) |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 1.5 Quality of life: St George's Respiratory Questionnaire or Clinical COPD Questionnaire total scores (26–52 weeks) |
2 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 1.5.1 Change to pharmacotherapy |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 1.5.2 Adherence aids |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 1.6 Hospital service utilisation: number of people admitted to hospital (all cause) (52 weeks) |
1 |
|
Odds Ratio (M‐H, Random, 95% CI) |
Totals not selected |
| 1.6.1 Change to pharmacotherapy |
1 |
|
Odds Ratio (M‐H, Random, 95% CI) |
Totals not selected |
| 1.7 Exacerbations: number of people experiencing exacerbations (16–52 weeks) |
2 |
267 |
Odds Ratio (M‐H, Random, 95% CI) |
0.87 [0.51, 1.50] |
| 1.7.1 Change to pharmacotherapy |
2 |
267 |
Odds Ratio (M‐H, Random, 95% CI) |
0.87 [0.51, 1.50] |
| 1.8 Adverse events: number of people experiencing adverse events (16–52 weeks) |
3 |
404 |
Odds Ratio (M‐H, Random, 95% CI) |
0.92 [0.60, 1.41] |
| 1.8.1 Adherence aids |
1 |
137 |
Odds Ratio (M‐H, Random, 95% CI) |
0.83 [0.38, 1.83] |
| 1.8.2 Change to pharmacotherapy |
2 |
267 |
Odds Ratio (M‐H, Random, 95% CI) |
1.04 [0.50, 2.17] |
| 1.9 Adverse events: number of people experiencing adverse events (COPD‐related) (52 weeks) |
1 |
|
Odds Ratio (M‐H, Random, 95% CI) |
Totals not selected |
| 1.9.1 Change to pharmacotherapy |
1 |
|
Odds Ratio (M‐H, Random, 95% CI) |
Totals not selected |
| 1.10 Adverse events: number of people experiencing a serious adverse event (26–52 weeks) |
2 |
350 |
Odds Ratio (M‐H, Random, 95% CI) |
1.57 [0.86, 2.87] |
| 1.10.1 Change to pharmacotherapy |
1 |
213 |
Odds Ratio (M‐H, Random, 95% CI) |
1.51 [0.74, 3.04] |
| 1.10.2 Adherence aids |
1 |
137 |
Odds Ratio (M‐H, Random, 95% CI) |
1.76 [0.55, 5.69] |
| 1.11 Mortality (52 weeks) |
1 |
|
Odds Ratio (M‐H, Random, 95% CI) |
Totals not selected |
| 1.11.1 Change to pharmacotherapy |
1 |
|
Odds Ratio (M‐H, Random, 95% CI) |
Totals not selected |
