| Antibodies |
| APC anti-mouse F4/80 antibody |
Miltenyl Biotec |
Cat# 130-116-525; RRID: AB_2733417 |
| APC/Cy7 anti-mouse/human CD11b antibody |
Biolegend |
Cat# 101225; RRID: AB_830641 |
| Biotin anti-mouse IL-12/IL-23 p40 antibody |
Biolegend |
Cat# 505301; RRID: AB_315373 |
| PE anti-mouse IL-23R antibody |
Biolegend |
Cat# 150903; RRID: AB_2572188 |
| FITC anti-mouse IL-17A antibody |
Miltenyl Biotec |
Cat# 130-102-262; RRID: AB_2660786 |
| Purified anti-mouse CD16/32 Antibody |
Biolegend |
Cat# 101302; RRID: AB_312801 |
| LEAF™ purified anti-mouse IL-17A antibody |
Biolegend |
Cat# 506906; RRID: AB_528927 |
| IL-17R antibody (G-9) |
Santa Cruz |
Cat# sc-376374; RRID: AB_10991331 |
| Biological Samples |
| Monkey DRG tissue |
Wake Forest University |
NA |
| Human DRG tissue |
National Disease Research interchange (NDRI) |
NA |
| Chemicals, Peptides, and Recombinant Proteins |
| Recombinant Mouse IL-23 protein |
Biolegend |
Cat# 589004 |
| Recombinant Mouse IL-12 protein |
Biolegend |
Cat# 577002 |
| Recombinant Mouse IL-17A protein |
Biolegend |
Cat# 576004 |
| Recombinant Cynomolgus monkey IL-17A protein |
R&D systems |
Cat# 10164-IL-050 |
| Recombinant Human IL-17A protein |
Biolegend |
Cat# 570504 |
| P2305: Peptide “TEEEEQQLY” |
Peptron (Quiniou et al., 2014) |
NA |
| Paclitaxel |
Sigma-Aldrich |
Cat# T7191 |
| Resiniferatoxin |
Sigma-Aldrich |
Cat# R8756 |
| AMG9801 |
Sigma-Aldrich |
Cat# A2731 |
| Capsaicin |
Sigma-Aldrich |
Cat# M2028 |
| QX-314 |
Sigma-Aldrich |
Cat# 552233 |
| Flagellin |
InvivoGen |
Cat# Tlrl-stfla |
| IB4-SAP |
Advanced targeting systems |
Cat# IT-10-25 |
| Saporin |
Advanced targeting systems |
Cat# SAP-25 |
| eBioscience Streptavidin FITC Conjugate |
Invitrogen |
Cat# 11-4317-87 |
| PPT |
Tocris Bioscience (Ji et al., 2011) |
Cat# 1426 |
| MPP |
Tocris Bioscienc (Zhong et al., 2010) |
Cat# 1991 |
| AC186 |
Tocris Bioscience (Ma et al., 2016) |
Cat# 5030 |
| Ailanthone |
Tocris Bioscience (He et al., 2016) |
Cat# 6161 |
| 17β-Estradiol (Estrogen) |
Cayman Chemical |
Cat# 10006315 |
| Testosterone |
Cayman Chemical |
Cat# 15645 |
| Critical Commercial Assays |
| Mouse IL-23 (p19/p40) ELISA kit |
Biolegend |
433707 |
| Mouse IL-17A/F heterodimer ELISA kit |
R&D systems |
DY5390 |
| Experimental Models: Organisms/Strains |
| Mouse: B6.129X1-Trpv1tm1Jul /J (Trpv1−/−) |
The Jackson Laboratory |
JAX: 003770 |
| Mouse: B6.129P-Trpa1tm1Kykw /J (Trpa1−/−) |
The Jackson Laboratory |
JAX: 006401 |
| Mouse: NOD.Cg-Prkdcscid / J (nude) |
The Jackson Laboratory |
JAX: 001303 |
| Mouse: B6.129S7-Rag1tm1Mom / J (Rag1−/−) |
The Jackson Laboratory |
JAX: 002216 |
| Mouse: B6.129-Trpv1tm1(cre)Bbm /J (TRPV1CRE) |
The Jackson Laboratory |
JAX: 017769 |
| Mouse: B6(Cg)-Esr1tm4.1Ksk /J (loxERα) |
The Jackson Laboratory |
JAX: 032173 |
| Mouse: C57BL/6J-Tg(Thy1-GCaMP6f)GP5.11Dkim /J |
The Jackson Laboratory |
JAX: 024339 |
| Mouse: C57BL/6J (Wildtype) |
The Jackson Laboratory |
JAX: 000664 |
| Mouse: CD1 |
Charles River Laboratories |
CRL:022 |
| Mouse: Il23−/−
|
Genentech (Shih et al., 2014) |
NA |
| Mouse: Il23r−/−
|
Genentech (Shih et al., 2014) |
NA |
| Mouse: AdvillinCre
|
Wang lab (Duke) (Hasegawa et al., 2007) |
JAX: 032536 | |
| Oligonucleotides |
| Primers for target genes, see Table S2
|
This paper |
NA |
| RNAscope probe: Mm-Il17ra
|
ACD |
Cat# 403741 |
| RNAscope probe: Mm-Trpv1-C2 |
ACD |
Cat# 313331-C2 |
| RNAscope probe: Mm-Esr1-C3 |
ACD |
Cat# 478201-C3 |
| Software and Algorithms |
| ANY-MAZE Software |
(Chamessian et al., 2019) |
https://www.anymaze.co.uk/
|
| BD FACSDiva™ Software |
(Bang et al., 2018) |
https://www.bdbiosciences.com/en-us/instruments/research-instruments/research-software/flow-cytometry-acquisition/facsdiva-software
|
| Cytobank Software |
(Bang et al., 2018) |
https://www.cytobank.org/
|
| Flowjo 10.4 |
(Chamessian et al., 2018) |
https://www.flowjo.com/
|
| QuPath Software |
(Wang et al., 2020b) |
https://qupath.github.io/
|
| pCLAMP 10.6 |
(Wang et al., 2020b) Axon |
https://mdc.custhelp.com/app/answers/detail/a_id/18779/~/axon%E2%84%A2pclamp%E2%84%A2-10-electrophysiology-data-acquisition-%26-analysis-software-download
|
| Prism 6 |
(Jiang et al., 2020) GraphPad |
https://www.graphpad.com/
|
