Figure 4.

Estimated postkidney transplantation change in overall symptom score by months since transplantation among recipients (n=521). Recipients were enrolled at admission for kidney transplantation. The overall symptom score ranged from zero to 100 points and was on the basis of self-reported burden of individual symptom/problem of kidney disease with five response options ranging from “not at all bothered” to “extremely bothered.” A higher symptom score represents a lower burden. Symptom burden was defined as very high: 0.0–71.0; high: 71.1–81.0; medium: 81.1–91.0; and low: 91.1–100.0. A knot was fit at 3 months post-transplantation on the basis of exploratory data analysis using lowess plots. The score was calculated from adjusted mixed effects models and was estimated for the “reference population” in which age is set to 65, sex is set to men, race is set to non-Black, diabetes status is set to nondiabetic, and time on dialysis is set to zero.