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Mechanisms of cisplatin-induced fibrosis after repeated low dose (7–9 mg/kg) cisplatin treatment. Solid line arrows indicate relationships directly examined in the literature. Dotted line arrows represent relationships studied in other models of renal fibrosis that we propose may also be occurring in the RLDC model. Supporting references: 25-30, 39-42, 47-49, and 61-67.
