Table 1.

Biometric parameters of sham and nondiabetic rats with myocardial-induced HF treated with the SGLT2 inhibitor empagliflozin or untreated

Biometric Parameters	Sham, n=16	Sham + EMPA, n=20	HF, n=14	HF + EMPA, n=17
Body weight, g	450±10	403±10a	398±5a	406±9b
Tibia length, mm	41.2±0.3	40.4±0.3	40.5±0.2	40.7±0.4
LV/tibia, mg/mm	20.4±0.8	17.6±0.4a	20.1±0.5c	20.6±0.4d
RV/tibia, mg/mm	6.26±0.24	5.22±0.16	8.90±0.96e, f	6.39±0.30g
LV + RV/tibia, mg/mm	26.7±1.1	22.8±0.5a	29.0±1.1f	27.0±0.6d
Lung/tibia, mg/mm	32.2±1.5	31.8±1.1	44.7±3.3e, f	31.7±1.7g
Lung water content, %	78.3±0.4	77.9±0.4	80.6±0.2e, f	79.1±0.3g
LK + RK/tibia, mg/mm	64±1	67±1	58±1a, f	67±1g

The values represent individual measurements and the means ± SEM. EMPA, empagliflozin; LK, left kidney; RK, right kidney.

^aP=0.005 versus sham.

^bP=0.01 versus sham.

^cP=0.01 versus sham + EMPA.

^dP=0.002 versus sham + EMPA.

^eP<0.001 versus sham.

^fP<0.001 versus sham + EMPA.

^gP<0.001 versus HF.