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Histograms show the relative florbetapir F18 signal in untreated (UT; n=3) and osteopathic cranial manipulative medicine (OCMM)–treated (n=3) aged rats. Normalized and averaged (mean [SE]) signals revealed a numerical reduction in amyloid β (Aβ) levels at midbrain (24.5% [2.4%]), ventral tegmental area (19.1% [2.6%]), hippocampus (13.4% [1.6%]), and whole brain (11.2% [2.9%]) of OCMM-treated UT rats.
