Fig 3.

COVID-19 outcomes by baseline IHG status. A,Top 3 plots: Kaplan-Meier curves for 30-day all-cause mortality from days since presentation by baseline IHG status (top), IHG-I and IHG-II subgrades (middle), and IHG-I and IHG-IV subgrades (bottom). Middle: Number at risk (No.) indicates patients who had not died or been censored before that time point. Bottom: Age-adjusted HRs (aHRs) with 95% CIs (reference: IHG-I). B,Top 3 plots: Cumulative hospital discharge estimates within 30 days of presentation among hospitalized patients by baseline IHG status (top), IHG-I and IHG-II subgrades (middle), and IHG-I and IHG-IV subgrades (bottom). Middle: Number at risk (No.) indicates patients who had not been discharged or been censored before that time point. Bottom: Age-adjusted RRs (aRRs) with 95% CIs (reference: IHG-I). C, Peak plasma IL-6 levels by hospitalization status, survivorship status in hospitalized patients, and baseline IHG status. D, Levels of SARS-CoV-2 viral transcript burden proxied by log₁₀-normalized counts of SARS-CoV-2 nucleoprotein “N” gene sequence in nasal transcriptomes of hospitalized patients by baseline IHG status, depicted as mean ± SEM (bands). H, Hospitalized; H-S, hospitalized survivor; H-NS, hospitalized nonsurvivor; NH, nonhospitalized; SEM, standard error of mean.