Figure 1.

Cytotoxic properties, invasiveness and the ability to form S. aureus-platelet-associates as mean ± SD of a S. aureus isolate collection (34 isolates) isolated from patients with approved IE (white, n = 24) as well as from nasal swabs of healthy individuals (gray, n = 10) (a). Principal component analysis (PCA) of pathogenic profiles using cytotoxicity, invasion and platelet-associates as principal components (PCs), explaining 100 % of the total variation. The analysis shows that the isolates of the two different collection sites (S. aureus IE and nasal swabs of healthy individuals) give comparable variation along the three PCs. Isolate 17, 30 and 33 differed most in their pathogenic profiles