Table 2.
Plasma Concentrations of LBP, CRP and ALT in MEC-APS participants by NAFLD status, overall and stratified by ethnicity
| NAFLD status |
||||
|---|---|---|---|---|
| No | Yes | Total | P | |
| All | N = 1033 | N = 511 | N = 1544 | |
| LBP | 22.4 (8.0) | 24.5 (8.3) | 22.2 (8.5) | < 0.001 |
| CRP | 1.60 (2.2) | 2.25 (2.8) | 1.82 (2.4) | < 0.001 |
| ALT | 19.6 (11.0) | 26.1 (14.3) | 21.7 (12.6) | < 0.001 |
| Japanese American | N = 222 | N = 178 | N = 400 | qa |
| LBP | 21.2 (7.5) | 22.6 (8.0) | 21.8 (7.8) | 0.865 |
| CRP | 0.8 (1.5) | 1.4 (1.8) | 1.1 (1.6) | 0.101 |
| ALT | 21.0 (9.6) | 28.9 (16.0) | 24.5 (13.4) | <0.001 |
| African American | N = 219 | N = 38 | N = 257 | |
| LBP | 22.9 (9.3) | 25.7 (9.9) | 23.3 (9.4) | 0.163 |
| CRP | 2.5 (2.9) | 4.1 (5.1) | 2.7 (3.4) | 0.051 |
| ALT | 18.9 (12.9) | 21.4 (9.3) | 19.3 (12.5) | 0.295 |
| White | N = 249 | N = 67 | N = 316 | |
| LBP | 22.2 (8.4) | 25.1 (7.5) | 22.8 (8.3) | 0.396 |
| CRP | 1.4 (1.7) | 2.9 (3.2) | 1.7 (2.2) | <0.001 |
| ALT | 19.1 (9.0) | 27.3 (15.2) | 20.8 (11.1) | <0.001 |
| Latino | N = 182 | N = 143 | N = 325 | |
| LBP | 22.4 (7.7) | 25.2 (8.4) | 23.6 (8.2) | 0.049 |
| CRP | 2.0 (2.3) | 2.7 (2.6) | 2.3 (2.5) | 0.132 |
| ALT | 19.1 (10.1) | 25.0 (13.6) | 21.7 (12.1) | <0.001 |
| Native Hawaiian | N = 161 | N = 85 | N = 246 | |
| LBP | 21.7 (7.5) | 24.2 (7.9) | 22.6 (7.7) | 0.227 |
| CRP | 1.3 (1.9) | 2.0 (2.5) | 1.5 (2.2) | 0.191 |
| ALT | 19.8 (13.3) | 23.5 (11.4) | 21.1 (12.7) | 0.024 |
Variables reported as mean (standard deviation).
at-test used
*Models were adjusted for ethnicity, sex, total fat mass, and batch.
Abbreviations and Units: LBP, lipopolysaccharide binding protein (mg/mL); CRP, C-reactive protein (mg/L) and ALT, alanine aminotransferase (U/L).