Table 1. Univariate Analyses for Patients Without HIT Compared to Patients With HIT.
Variable | Patients without HIT (N = 12,406) | Patients with HIT (N = 12,406) | P value |
---|---|---|---|
Age | 64.8 ± 15.5 | 64.8 ± 15.5 | 1.000 |
Gender - female | 6,091 (49.1%) | 6,091 (49.1%) | 1.000 |
Obesity | 1,590 (12.8%) | 2,188 (17.6%) | < 0.0005* |
Solid tumor without metastases | 313 (2.5%) | 438 (3.5%) | < 0.0005* |
Metastatic cancer | 309 (2.5%) | 515 (4.2%) | < 0.0005* |
Lymphoma | 141 (1.1%) | 130 (1.0%) | 0.502 |
Uncomplicated diabetes | 2,774 (22.4%) | 3,205 (25.8%) | < 0.0005* |
Diabetes with chronic complications | 733 (5.9%) | 1,280 (10.3%) | < 0.0005* |
Drug abuse | 523 (4.2%) | 439 (3.5%) | 0.006* |
Renal failure | 1,875 (15.1%) | 4,152 (33.5%) | < 0.0005* |
AIDS | 35 (0.3%) | 35 (0.3%) | 1.000 |
Primary hypercoagulable states | 39 (0.3%) | 416 (3.4%) | < 0.0005* |
Major surgery | 2,992 (24.1%) | 4,533 (36.5%) | < 0.0005* |
Congestive heart failure | 1,304 (10.5%) | 2,560 (20.6%) | < 0.0005* |
Autoimmune disease | 256 (2.1%) | 489 (3.9%) | < 0.0005* |
*P < 0.05 statistically significant. HIT: heparin-induced thrombocytopenia; AIDS: acquired immunodeficiency syndrome.