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. 2021 Aug 4;10(4):171–177. doi: 10.14740/jh876

Table 1. Univariate Analyses for Patients Without HIT Compared to Patients With HIT.

Variable Patients without HIT (N = 12,406) Patients with HIT (N = 12,406) P value
Age 64.8 ± 15.5 64.8 ± 15.5 1.000
Gender - female 6,091 (49.1%) 6,091 (49.1%) 1.000
Obesity 1,590 (12.8%) 2,188 (17.6%) < 0.0005*
Solid tumor without metastases 313 (2.5%) 438 (3.5%) < 0.0005*
Metastatic cancer 309 (2.5%) 515 (4.2%) < 0.0005*
Lymphoma 141 (1.1%) 130 (1.0%) 0.502
Uncomplicated diabetes 2,774 (22.4%) 3,205 (25.8%) < 0.0005*
Diabetes with chronic complications 733 (5.9%) 1,280 (10.3%) < 0.0005*
Drug abuse 523 (4.2%) 439 (3.5%) 0.006*
Renal failure 1,875 (15.1%) 4,152 (33.5%) < 0.0005*
AIDS 35 (0.3%) 35 (0.3%) 1.000
Primary hypercoagulable states 39 (0.3%) 416 (3.4%) < 0.0005*
Major surgery 2,992 (24.1%) 4,533 (36.5%) < 0.0005*
Congestive heart failure 1,304 (10.5%) 2,560 (20.6%) < 0.0005*
Autoimmune disease 256 (2.1%) 489 (3.9%) < 0.0005*

*P < 0.05 statistically significant. HIT: heparin-induced thrombocytopenia; AIDS: acquired immunodeficiency syndrome.