TABLE 2.
Composition of the contrasted experience by heart recipient sex and age among recipients of a female donor (N = 21550)
| 0–12 y | 13–24 y | 25–44 y | ≥45 y | |||||
|---|---|---|---|---|---|---|---|---|
| Females (MF) | Males (MM) | Females (MF) | Males (MM) | Females (MF) | Males (MM) | Females (MF) | Males (MM) | |
| Person-y of observation | 7079 | 8538 | 6087 | 7826 | 10 702 | 9535 | 41 928 | 66 681 |
| Retransplants | 60 | 44 | 62 | 72 | 67 | 68 | 92 | 128 |
| Deaths after failure | 133 | 154 | 134 | 144 | 200 | 186 | 471 | 764 |
| Age at transplant (y) | ||||||||
| Median (IQR) | 0 (0–2) | 0 (0–3) | 12 (6–16) | 12 (6–16) | 32 (25–37) | 31 (23–37) | 55 (49–60) | 56 (50–62) |
| Race (%) | ||||||||
| White | 76.4 | 80.9 | 76.7 | 77.5 | 72.6 | 76.1 | 78.6 | 87.8 |
| Black | 16.8 | 14.9 | 17.7 | 18.6 | 24.0 | 20.2 | 19.1 | 10.0 |
| Other | 6.9 | 4.2 | 5.6 | 3.9 | 3.4 | 3.7 | 2.4 | 2.2 |
| Primary disease (%) | ||||||||
| Congenital heart disease | 45.7 | 58.5 | 33.5 | 35.0 | 13.9 | 11.3 | 5.3 | 3.3 |
| Cardiomyopathy | 45.6 | 33.8 | 55.4 | 53.3 | 67.6 | 65.9 | 63.6 | 36.6 |
| Coronary/ischemic | 0.5 | 0.7 | 1.0 | 1.2 | 8.0 | 13.5 | 25.2 | 57.5 |
| Myocarditis | 5.1 | 3.4 | 5.4 | 5.7 | 4.0 | 5.8 | 2.4 | 1.3 |
| Others | 3.2 | 3.5 | 4.6 | 4.2 | 6.0 | 3.1 | 3.3 | 1.1 |
| Missing (%) | 0.0 | 0.1 | 0.2 | 0.5 | 0.5 | 0.3 | 0.3 | 0.2 |
| Insurer (%) | ||||||||
| Private | 40.4 | 42.0 | 43.5 | 47.6 | 42.5 | 42.8 | 46.4 | 44.7 |
| Public | 41.4 | 41.8 | 34.2 | 32.3 | 29.6 | 29.7 | 29.0 | 29.3 |
| No coverage | 2.2 | 1.2 | 2.1 | 1.3 | 1.9 | 1.2 | 1.1 | 0.7 |
| Missing | 16.0 | 15.0 | 20.3 | 18.9 | 26.0 | 26.4 | 23.5 | 25.3 |
| Era (%) | ||||||||
| 1988–1994 | 17.8 | 17.4 | 22.1 | 21.7 | 28.0 | 28.4 | 27.1 | 27.5 |
| 1995–1999 | 15.4 | 18.8 | 21.5 | 20.5 | 19.7 | 17.2 | 22.6 | 21.8 |
| 2000–2004 | 17.2 | 17.1 | 20.7 | 18.1 | 20.0 | 17.6 | 19.6 | 19.0 |
| 2005–2009 | 22.5 | 20.1 | 18.2 | 17.8 | 15.6 | 17.1 | 16.3 | 16.1 |
| 2010–2014 | 19.4 | 18.4 | 13.2 | 15.8 | 12.5 | 13.2 | 10.9 | 11.2 |
| 2015–2019 | 7.7 | 8.2 | 4.2 | 6.2 | 4.3 | 5.9 | 3.6 | 4.4 |
| Ventricular assist device | 9.2 | 7.2 | 11.8 | 12.7 | 19.6 | 18.7 | 14.3 | 15.5 |
| Medical condition | ||||||||
| ICU | 58.0 | 57.9 | 50.0 | 47.1 | 43.7 | 41.4 | 38.2 | 38.3 |
| Hospitalized/not ICU | 13.7 | 11.7 | 14.0 | 14.2 | 15.3 | 16.5 | 13.7 | 14.0 |
| Not hospitalized | 28.3 | 30.4 | 36.0 | 38.6 | 40.8 | 42.0 | 48.0 | 47.5 |
| Missing (%) | 0.0 | 0.1 | 0.0 | 0.1 | 0.2 | 0.1 | 0.2 | 0.2 |
| Donor:recipient weight ratio | ||||||||
| Median (IQR) | 1.4 (1.1–1.7) | 1.4 (1.1–1.8) | 1.2 (1.0–1.5) | 1.2 (1.0–1.5) | 1.0 (0.9–1.2) | 1.0 (0.9–1.2) | 1.0 (0.9–1.2) | 1.0 (0.8–1.1) |
| Missing (%) | 6.0 | 6.0 | 7.4 | 7.7 | 8.5 | 12.3 | 7.0 | 10.1 |
| Donor age (y) | ||||||||
| Median (IQR) | 1 (0–4) | 1 (0–4) | 15 (7–22) | 15 (5–22) | 29 (18–39) | 29 (19–40) | 34 (21–44) | 35 (23–45) |
| Missing (%) | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| HLA MM | ||||||||
| Median (IQR) | 5 (4–5) | 5 (4–5) | 5 (4–5) | 5 (4–5) | 5 (4–5) | 5 (4–5) | 5 (4–5) | 5 (4–5) |
| Missing (%) | 21.1 | 23.1 | 19.3 | 22.1 | 15.5 | 19.1 | 14.0 | 15.7 |
| Donor race | ||||||||
| White (%) | 76.7 | 73.4 | 80.1 | 79.3 | 81.3 | 83.9 | 83.7 | 85.3 |
| Black (%) | 20.3 | 23.8 | 16.7 | 18.9 | 16.6 | 14.2 | 13.7 | 12.9 |
| Other (%) | 3.0 | 2.8 | 3.2 | 1.9 | 2.2 | 1.9 | 2.6 | 1.8 |
FF, female donor–female recipient; FM, female donor–male recipient; ICU, intensive care unit; IQR, interquartile range; MF, male donor–female recipient; MM, male donor–male recipient.