Skip to main content
. 2021 Jul 11;8(17):2101230. doi: 10.1002/advs.202101230

Figure 4.

Figure 4

High degree of ITH exhibited by the IDH mutation subgroup A) Unsupervised hierarchical clustering of genes related to chromatin modifier and metabolism across ICC samples. ITH status, IDH mutation, IDH‐SG, and patient ID are annotated. B) 33 cases from ICC_TCGA. ITH status, IDH mutation, IDH‐SG, and patient ID are annotated. C) Bar plot comparing the number of IDH‐SG patients in the groups of high‐ITH and low‐ITH patients in ICC_this study (left) and ICC_TCGA (right). *: P < 0.05, ***: P < 0.001, Chi‐square test. D) Box plot comparing the clonal‐ITH of IDH‐SG and IDH‐NO patients in ICC_this study (left) and ICC_TCGA (right). *: P < 0.05, ***: P < 0.001, Chi‐square test.