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IDH mutation subgroup exhibited a distinct tumor microenvironment. A) Unsupervised hierarchical clustering of CD8+ T cell‐related markers in our study. B) Heatmap of CD8+ T cell‐related markers in the ICC_TCGA study. Boxplots comparing the expression of CD8+ T cell‐related markers between IDH‐SG and IDH‐NO patients C) in our study and D) the ICC_TCGA study. *: P < 0.05, **: P < 0.05, ***: P < 0.001, Student's t test. E) IHC of CD8 for six patients. Scale bar, 200 µm.
