Table 2.

Correlations between regional PET uptake and sleep variables of interest^a

	Correlation with entorhinal FTP SUVR (r)	Correlation with meta-ROI FTP SUVR (r)	Correlation with cortical PiB DVR (r)
Actigraphy-measured sleep
Global actigraphy composite	−0.23*	−0.31**	−0.01
Sleep duration	−0.08	−0.11	−0.03
Sleep efficiency	−0.18	−0.29**	0.02
Sleep fragmentation	0.11	0.19	−0.07
Self-reported sleep
PSQI global	0.34***	0.28**	0.36***
Sleep duration	−0.18	−0.07	−0.13
Sleep efficiency	−0.18	−0.16	−0.28**

^aColumns represent each brain ROI. Rows represent two-sided bivariate correlations between sleep metric and PET uptake (see Materials and Methods). PiB DVR ROIs are comprised of weighted PiB DVR means within FreeSurfer regions as described by Villeneuve et al. (2015). FTP SUVR ROIs are comprised of weighted FTP SUVR means within FreeSurfer regions after PVC, as described by Maass et al. (2017).

*p < 0.05;

**p < 0.01;

***p < 0.001; significant r value.