FIG. 11.

Complementation of I1A cells with IRAK2. E-selectin–Luc was cotransfected transiently with control vector, MyD88, or TRAF6 into I1A cells stably transfected with CMV-IRAK2 (I1A-IRAK2 cells). The I1A-IRAK2 cells transfected with E-selectin–Luc and the control vector were treated with IL-1 (100 U/ml, 4 h). Data are presented as the fold induction of luciferase activity in IL-1-treated or untreated cells transfected with MyD88 or TRAF6 compared to cells transfected with the control vector. Shown are the averages and standard deviations from three independent experiments.