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. 2021 Aug 21;24(9):103015. doi: 10.1016/j.isci.2021.103015

Figure 3.

Figure 3

NE depolarizes PVT neurons in brain slice recording

(A) A representative neuron shows that NE (5 μM) increases the activity of PVT neurons.

(B and C) Statistical comparison of the membrane potential (B) and firing frequency (C) after application of 5 μM NE. Two-tailed paired t test, ∗∗∗p < 0.001, n = 25 neurons.

(D) A representative neuron shows that NE (5 μM) increases the activity of PVT neurons in the presence of 5 μM sulpiride (SUL).

(E and F) Statistical comparison of the membrane potential (E) and firing frequency (F) after application of 5 μM NE in the presence of 5 μM SUL. Two-tailed paired t test, ∗∗p < 0.01, n = 7 neurons. Data are represented as mean ± SEM.