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. 2021 Sep 9;21:345. doi: 10.1186/s12883-021-02378-3

Table 2.

Migraine treatment of users included in the study

Overall (N = 163,176) Stress-related migraine (N = 84,740) Non stress-related migraine (N = 78,436) p
Medical characteristics
 Acute treatment (OTC)
  Total, number (% of subjects) 102,676 (63%) 62,325 (74%) 40,351 (48%) < 0.0001
  Ibuprofen, number (% of reported) 57,032 (56%) 36,163 (58%) 20,869 (52%)
  Acetaminophen, number (% of reported) 56,704 (55%) 36,164 (58%) 20,540 (51%)
  Naproxen, number (% of reported) 15,656 (15%) 10,370 (17%) 5286 (13%)
  Acetylsalicylic acid, number (% of reported) 4074 (4%) 2690 (4%) 1384 (3%)
  Ketorolac, number (% of reported) 3684 (4%) 2538 (4%) 1146 (3%)
Acute treatment (prescription)
 Total, number (% of subjects) 65,846 (40%) 42,056 (50%) 23,790 (28%) < 0.0001
  Sumatriptan, number (% of reported) 27,390 (42%) 17,684 (42%) 9706 (41%)
  Rizatriptan, number (% of reported) 17,347 (26%) 11,150 (27%) 6197 (26%)
  Ondansetron, number (% of reported) 5474 (8%) 3914 (9%) 1560 (7%)
  Eletriptan, number (% of reported) 4364 (7%) 2847 (7%) 1517 (6%)
  Zolmitriptan, number (% of reported) 4349 (7%) 2827 (7%) 1522 (6%)
Preventive treatment
 Total, number (% of subjects) 27,029 (16.6%) 17,993 (21%) 9036 (11%) < 0.0001
  Topiramate, number (% of reported) 7950 (29%) 4980 (28%) 2970 (33%)
  Erenumab, number (% of reported) 3721 (14%) 2489 (14%) 1232 (14%)
  Botox, number (% of reported) 2532 (9%) 1803 (10%) 729 (8%)
  Galcanezumab, number (% of reported) 2250 (8%) 1594 (9%) 656 (7%)
  Propranolol, number (% of reported) 1899 (7%) 1310 (7%) 589 (7%)