. Author manuscript; available in PMC: 2022 Jul 6.

Published in final edited form as: Biometrics. 2021 Mar 22;78(2):460–473. doi: 10.1111/biom.13451

Table 2.

Application results of Cox model. Event time is years from AD symptom onset to death. The proposed EM estimator, which adjusts for double truncation and dependence is denoted by ${\hat{β}}_{e m}$ . The weighted methods of Rennert and Xie (2018b) and Mandel et al. (2018) adjust for double truncation but assume independence, and are denoted by ${\hat{β}}_{w}$ and ${\hat{β}}_{w_{o}}$ , respectively. The standard method, denoted by ${\hat{β}}_{s}$ , does not account for truncation or dependence.

	Estimator
Variable	Standard		Weighted		Weighted (offset)		EM

	${\hat{β}}_{s} (\hat{SE})$	95% CI	${\hat{β}}_{w} (\hat{SE})$	95% CI	${\hat{β}}_{w_{0}} (\hat{SE})$	95% CI	${\hat{β}}_{e m} (\hat{SE})$	95% CI

Age onset	0.04 (0.01)	(0.03,0.06)	0.06 (0.01)	(0.03,0.08)	0.05 (0.01)	(0.03,0.07)	0.06 (0.01)	(0.03,0.08)
Female	−0.48 (0.15)	(−0.70,−0.16)	−0.57 (0.22)	(−0.91,−0.12)	−0.55 (0.20)	(−0.87,−0.15)	−0.61 (0.17)	(−0.82,−0.23)
MMSE	−0.03 (0.01)	(−0.04,−0.01)	−0.03 (0.01)	(−0.06,−0.01)	−0.03 (0.01)	(−0.05,−0.01)	−0.05 (0.01)	(−0.07,−0.03)
Occupation	0.20 (0.28)	(−0.37,0.75)	0.39 (0.41)	(−0.35,1.26)	0.37 (0.40)	(−0.38,1.11)	0.21 (0.29)	(−0.41,0.76)