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. 2021 Aug 26;12:721013. doi: 10.3389/fimmu.2021.721013

Figure 3.

Figure 3

The performance of various markers on CD4+ T cells in distinguishing ATB patients from LTBI individuals in Qiaokou cohort. (A) Scatter dot plots showing the results of the expression of HLA-DR, CD38, CD69, CD25, and CD27 on CD4+ T cells in ATB patients and LTBI individuals. Horizontal lines indicate the medians. (B) ROC analysis showing the performance of the expression of CD38 and CD25 on CD4+ T cells in discriminating ATB patients from LTBI individuals. (C) Scatter dot plots showing the results of the proportions of HLA-DR+CD27- cells, HLA-DR-CD27+ cells, CD38+CD27- cells, CD38-CD27+ cells, CD25+CD27- cells, and CD25-CD27+ cells of CD4+ T cells in ATB patients and LTBI individuals. Horizontal lines indicate the medians. *P < 0.05, **P < 0.01, ns, no significance (Mann-Whitney U test). MTB, Mycobacterium tuberculosis; ATB, active tuberculosis; LTBI, latent tuberculosis infection; AUC, area under the curve.