Table 3.
The effect of sorafenib formulations on nude mice’s body weight and main organs mass.
| Main organs mass | Control | Sol-Sol | Sol-Oral | Sol-MS |
|---|---|---|---|---|
| Body weight (g) | 21.15 ± 1.92 | 20.20 ± 2.09 | 11.86 ± 2.81 | 21.44 ± 2.45 |
| Heart (mg) | 110.79 ± 6.63 | 108.44 ± 1368 | 59.93 ± 2.80 | 109.65 ± 7.18 |
| Liver (mg) | 677.05 ± 37.09 | 658.20 ± 21.15 | 364.60 ± 7.56 | 660.00 ± 43.11 |
| Spleen (mg) | 17.64 ± 0.43 | 17.11 ± 0.83 | 9.45 ± 0.78 | 16.57 ± 0.27 |
| Double kidney (mg) | 257.92 ± 8.45 | 248.21 ± 11.94 | 169.06 ± 20.49 | 250.27 ± 16.11 |
| Lung (mg) | 176.37 ± 46.73 | 181.67 ± 33.29 | 115.02 ± 12.56 | 165.89 ± 18.44 |