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. 2021 Aug 26;12:695373. doi: 10.3389/fimmu.2021.695373

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Copyright © 2021 Oulee, Ma, Teles, de Andrade Silva, Pellegrini, Klechevsky, Harman, Rhodes and Modlin

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Genes upregulated in LCs after activation with TNF. Boxplots showing the expression of (A) ADM, (B) CCL17, (C) CCL19, (D) CXCL2, (E) CCL2, and (F) CCL1, encoding antimicrobial peptides in LCs prior to (0h) and at various time points following activation with TNF in transcriptomes 4 and 7. Genes shown above were identified in at least two instances, either in multiple transcriptomes experiments or in one transcriptome experiment but also identified in LCs in non-transcriptome experiments in the literature. *p < 0.05, **p < 0.01, ***p < 0.001.