Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 8;11:17842. doi: 10.1038/s41598-021-96262-2

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

The effect of BzATP treatment on the expression and production of pro-inflammatory cytokines in monocyte-generated macrophages from patients and controls. BzATP significantly increased the mRNA expression level of TNFA in AS and healthy macrophages. The production level of TNF-α was also significantly upregulated after BzATP treatment in both groups and monocyte-generated macrophages from AS patients significantly produced a higher amount of TNF-α after treatment compared to control ones. Besides, BzATP significantly elevated the expression level of IL1B in monocyte-derived macrophages from both patients and controls. The data are presented as the mean ± SEM (*P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001).