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. 2021 Sep 8;11:17823. doi: 10.1038/s41598-021-97140-7

Table 2.

Best results of association analysis of HLA with response to Li as continuous trait for group GWAS1 in additive model.

HLA protein, position, amino-acid(s) Freq (%) GWAS1 (N = 772) Beta GWAS1 P-value GWAS1 Q-value GWAS1
HLA-DRB1, 37, tyrosine and leucine 33.35 0.57 4.78 × 10−4 0.12
HLA-DRB1, 71, arginine 50.06 0.51 6.78 × 10−4 0.12
HLA-DQB1, 26, leucine 68.8  − 0.53 8.30 × 10−4 0.12
HLA-DRB1, 67, phenylalanine 16.65 0.68 9.80 × 10−4 0.12

Freq: frequency; Q-value: the q-value gives the expected positive false discovery rate.