Table 4.
Country by country distribution of the patients carrying the HLA-DRB1 alleles A or L at position 74.
| City/Country | N | A/L Allele frequency | Recessive model | Dominant model | ||||
|---|---|---|---|---|---|---|---|---|
| Non- resp | Resp | Non-resp (%) | Resp (%) | Non-resp (%) | Resp (%) | Non-resp (%) | Resp (%) | |
| GWAS1 | ||||||||
| Cagliari/Italy | 52 | 91 | 63.46 | 71.43 | 38.46 | 51.65 | 88.46 | 91.21 |
| Halifax/Canada | 55 | 150 | 58.18 | 71.00 | 32.73 | 52.00 | 83.64 | 90.00 |
| San Diego/USA | 79 | 58 | 68.99 | 75.00 | 46.84 | 62.07 | 91.14 | 87.93 |
| Wuerzburg/Germany | 25 | 30 | 62.00 | 76.67 | 36.00 | 56.67 | 88.00 | 96.67 |
| GWAS2 | ||||||||
| Barcelona/Spain | 19 | 40 | 50.00 | 65.00 | 21.05 | 40.00 | 78.95 | 90.00 |
| Canada | 17 | 52 | 67.65 | 65.38 | 35.29 | 42.31 | 100.00 | 88.46 |
| Paris/France | 47 | 114 | 62.77 | 71.05 | 34.04 | 50.88 | 91.49 | 91.23 |
| Romania | 18 | 82 | 77.78 | 79.27 | 55.56 | 59.76 | 100.00 | 98.78 |
| Sweden | 39 | 200 | 71.79 | 77.25 | 51.28 | 59.50 | 92.31 | 95.00 |
Non-resp = Li non responders (ALDA subscale A less than or equal to 3); Resp = Li responders (ALDA subscale A greater than or equal to 7); N = number of patients in the group; recessive model = percentage of patients carrying only the A or L allele; dominant model = percentage of patients carrying at least one allele A or L.