Table 2.

Prolactin levels from baseline through week 16 in men with TRS.

Variable		ARI (N = 100)	vB6 (N = 100)	P
Change in serum prolactin from baseline (μg/L)	Week 4	−33.01 ± 8.05	−35.80 ± 13.71	0.08
	Week 8	−35.70 ± 8.01	−45.97 ± 14.47	<0.001
	Week 12	−33.62 ± 8.08	−54.33 ± 16.41	<0.001
	Week 16	−33.29 ± 7.80	−65.09 ± 19.48	<0.001
Proportion with prolactin <40 μg/ml	Week 4	1 (1.0)	7 (7.0)	0.06
	Week 8	2 (2.0)	22 (22.0)	<0.001
	Week 12	1 (1.0)	48 (48.0)	<0.001
	Week 16	2 (2.0)	67 (67.0)	<0.001

MMRM showed a significant group × time interaction effect on prolactin level (F = 112.63, p < 0.001).