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. 2021 Aug 26;11:735940. doi: 10.3389/fonc.2021.735940

Figure 2.

Figure 2

Clonogenic survival of G0/G1-phase normal NFF28 primary fibroblasts (A) and asynchronously growing A549 lung carcinoma (B), U2OS osteosarcoma (C), and U87MG malignant glioma cells (D) pretreated for 18 h with 10 µM SAHA, 10 µM M344, or 5 µM PTACH and exposed to 0.5–4 Gy 200 MeV protons in the Bragg plateau region (LET = 0.45 keV/µm). Data reported as mean ± SD; where error bars are not visible, they are smaller than the data point. Asterisks mark significant differences compared to DMSO controls at p-values of ≤0.05 (*) by one-way ANOVA.