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. 2022 Oct 6:10.1002/acr.24768. Online ahead of print. doi: 10.1002/acr.24768

Table 1.

Baseline characteristics of study patients*

Characteristic Group A Group B P
(n = 126) (n = 124)
Sex, female 97 (77) 94 (75.8) 0.826
Age at JIA onset, median (IQR) years 4 (2.2–6.8) 4.2 (2.0–6.9) 0.71
Age at V1, median (IQR) years§ 10.9 (7.8–14.4) 10.9 (8.0–14.4) 0.933
Disease duration at V1, median (IQR) years§ 5.1 (3.2–8.6) 5.3 (2.7–8.5) 0.809
JIA subtype
Oligoarticular 83 (65.8) 77 (62.1) 0.534
Polyarticular 35 (27.8) 41 (33.1) 0.364
Systemic 7 (5.6) 4 (3.2) 0.369
ERA 1 (0.8) 2 (1.6) 0.62
ANA positivity 58 (46) 52 (41.9) 0.514
History of uveitis 28 (22.2) 26 (21) 0.81
Past JIA treatment
Intraarticular glucocorticoid injections 45 (35.7) 40 (32.3) 0.564
Systemic glucocorticoids 21 (16.7) 18 (14.5) 0.639
Methotrexate 54 (42.9) 65 (52.4) 0.13
Other conventional DMARDs 3 (2.4) 2 (1.6) 1.0
Biologic DMARDs 14 (11.1) 16 (12.9) 0.663
Ongoing JIA treatment at V1§
NSAIDs 17 (13.5) 8 (6.5) 0.064
Systemic glucocorticoids 0 1 (0.8) 0.496
Methotrexate 59 (46.8) 46 (37.1) 0.119
Sulfasalazine 1 (0.8) 2 (1.6) 0.62
Biologic DMARDs 55 (43.7) 56 (45.2) 0.81
Etanercept 28 (22.2) 27 (21.8) 0.932
Adalimumab 15 (11.9) 14 (11.3) 0.879
Infliximab 2 (1.6) 3 (2.4) 0.682
Tocilizumab 7 (5.6) 9 (7.3) 0.582
Canakinumab 0 1 (0.8) 0.496
Abatacept 3 (2.4) 2 (1.6) 1.0
Off‐therapy 20 (15.9) 28 (22.6) 0.178
Out‐of‐school physical activity in the last month, no./total no. (%)# 50/91 (54.9) 50/92 (54.3) 0.9
*

Values are the number (%) unless indicated otherwise. ANA = antinuclear antibody; DMARDs = disease‐modifying antirheumatic drugs; ERA = enthesitis‐related arthritis; IQR = interquartile range; JIA = juvenile idiopathic arthritis; NSAIDs = nonsteroidal antiinflammatory drugs.

By chi‐square test unless otherwise specified.

By Mann‐Whitney U test.

§

V1 frame was from September 1, 2018 to March 9, 2019 in group A; and from September 1, 2019 to March 9, 2020 in group B.

By Fisher's exact test.

#

Data on sports activity outside school were available for 91 patients in group 1 and for 92 patients in group 2.