Table 1.
Characteristic | Group A | Group B | P † |
---|---|---|---|
(n = 126) | (n = 124) | ||
Sex, female | 97 (77) | 94 (75.8) | 0.826 |
Age at JIA onset, median (IQR) years | 4 (2.2–6.8) | 4.2 (2.0–6.9) | 0.71‡ |
Age at V1, median (IQR) years§ | 10.9 (7.8–14.4) | 10.9 (8.0–14.4) | 0.933‡ |
Disease duration at V1, median (IQR) years§ | 5.1 (3.2–8.6) | 5.3 (2.7–8.5) | 0.809‡ |
JIA subtype | |||
Oligoarticular | 83 (65.8) | 77 (62.1) | 0.534 |
Polyarticular | 35 (27.8) | 41 (33.1) | 0.364 |
Systemic | 7 (5.6) | 4 (3.2) | 0.369 |
ERA | 1 (0.8) | 2 (1.6) | 0.62¶ |
ANA positivity | 58 (46) | 52 (41.9) | 0.514 |
History of uveitis | 28 (22.2) | 26 (21) | 0.81 |
Past JIA treatment | |||
Intraarticular glucocorticoid injections | 45 (35.7) | 40 (32.3) | 0.564 |
Systemic glucocorticoids | 21 (16.7) | 18 (14.5) | 0.639 |
Methotrexate | 54 (42.9) | 65 (52.4) | 0.13 |
Other conventional DMARDs | 3 (2.4) | 2 (1.6) | 1.0¶ |
Biologic DMARDs | 14 (11.1) | 16 (12.9) | 0.663 |
Ongoing JIA treatment at V1§ | |||
NSAIDs | 17 (13.5) | 8 (6.5) | 0.064 |
Systemic glucocorticoids | 0 | 1 (0.8) | 0.496¶ |
Methotrexate | 59 (46.8) | 46 (37.1) | 0.119 |
Sulfasalazine | 1 (0.8) | 2 (1.6) | 0.62¶ |
Biologic DMARDs | 55 (43.7) | 56 (45.2) | 0.81 |
Etanercept | 28 (22.2) | 27 (21.8) | 0.932 |
Adalimumab | 15 (11.9) | 14 (11.3) | 0.879 |
Infliximab | 2 (1.6) | 3 (2.4) | 0.682¶ |
Tocilizumab | 7 (5.6) | 9 (7.3) | 0.582 |
Canakinumab | 0 | 1 (0.8) | 0.496¶ |
Abatacept | 3 (2.4) | 2 (1.6) | 1.0¶ |
Off‐therapy | 20 (15.9) | 28 (22.6) | 0.178 |
Out‐of‐school physical activity in the last month, no./total no. (%)# | 50/91 (54.9) | 50/92 (54.3) | 0.9 |
Values are the number (%) unless indicated otherwise. ANA = antinuclear antibody; DMARDs = disease‐modifying antirheumatic drugs; ERA = enthesitis‐related arthritis; IQR = interquartile range; JIA = juvenile idiopathic arthritis; NSAIDs = nonsteroidal antiinflammatory drugs.
By chi‐square test unless otherwise specified.
By Mann‐Whitney U test.
V1 frame was from September 1, 2018 to March 9, 2019 in group A; and from September 1, 2019 to March 9, 2020 in group B.
By Fisher's exact test.
Data on sports activity outside school were available for 91 patients in group 1 and for 92 patients in group 2.