TABLE 1.
PROMs, Sniffin’ Sticks scores, 10 and percentage of normosmic, hyposmic, and anosmic patients at T0, T1, and T2
| Parameter | T0 (n = 101) | T1 (n = 83) | T2 (n = 22) | p T0 versus T1 a | p T1 versus T2 a |
|---|---|---|---|---|---|
| sVAS, mean ± SD | 2.33 ± 3.18 | 6.35 ± 3.05 | 7.20 ± 2.71 | <0.0001 | 0.0394 |
| tVAS, mean ± SD | 3.31 ± 3.46 | 7.39 ± 2.63 | 8.30 ± 1.90 | <0.0001 | 0.1614 |
| SNOT‐22, mean ± SD | 41.73 ± 18.24 | 16.12 ± 13.86 | 15.09 ± 11.74 | <0.0001 | 0.1262 |
| NS SNOT‐22, mean ± SD | 7.62 ± 5.46 | 2.76 ± 4.06 | 2.60 ± 3.99 | <0.0001 | 0.1819 |
| Threshold (T), mean ± SD | – | 5.90 ± 3.10 | 5.68 ± 2.71 | – | 0.0557 |
| Discrimination (D), mean ± SD | – | 11.20 ± 2.90 | 12.18 ± 1.53 | – | 0.0009 |
| Identification (I), mean ± SD | – | 11.50 ± 2.40 | 12.59 ± 1.44 | – | 0.0034 |
| TDI score, mean ± SD | – | 28.50 ± 6.50 | 30.34 ± 4.27 | – | <0.0001 |
| Normosmic, n (%) | – | 36 (43.4) | 11 (50.0) | – | – |
| Hyposmic, n (%) | – | 45 (54.2) | 11 (50.0) | – | – |
| Anosmic, n (%) | – | 2 (2.4) | 0 (0.0) | – | – |
Notes: sVAS/tVAS score range: 0 = the worst thinkable situation, 10 = not affected. NS SNOT‐22 items: (1) need to blow nose, (2) sneezing, (3) runny nose, (4) postnasal discharge, (5) thick nasal discharge, and (6) blockage/congestion of nose. TDI score: threshold + discrimination + identification.
Abbreviations: NS SNOT‐22, SNOT‐22 nasal symptoms items without considering those related to smell and taste dysfunctions; PROM, patient‐reported outcome measure; SD, standard deviation; SNOT‐22, 22‐item Sino‐Nasal Outcome Test; VAS, visual analogue scale; sVAS, VAS for smell; tVAS, VAS for taste; T0, subjects’ enrollment; T1, first olfactory evaluation; T2, second olfactory evaluation.
Significant p values are in bold. Level of significance p < 0.05.