Table 1.
Detection of SARS‐CoV‐2 RNA in ONPS, gargle samples in PCR media, and gargle samples in lysis buffer, using the Cobas® 6800/8800 SARS‐CoV‐2 test (n = 647)
| ONPS | Agreement a (95% CI) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Sample | POS | NEG | Invalid | Positive | Negative | Total | κ | ||
| Gargle in PCR Media | POS | 116 | 5 | 2 | 89.9 (83.4–94.1) |
99.0 (97.7–99.7) |
97.2% (95.6–98.3) |
0.91 (0.86–0.94) |
|
| NEG | 13 | 511 | 0 | ||||||
| Invalid | 0 | 0 | 0 | ||||||
| Gargle in lysis buffer | POS | 117 | 4 | 2 |
90.7 (84.3–94.7) |
99.2 (97.9–99.8) |
97.4% (95.8–98.4) |
0.92 (0.87–0.95) |
|
| NEG | 12 | 511 | 0 | ||||||
| Invalid | 0 | 1 | 0 | ||||||
Abbreviations: CI, confidence interval (calculated using exact Clopper‐Pearson test); PCR, polymerase chain reaction; ONPS, oropharyngeal/nasopharyngeal swab.
a
Invalid results were excluded from calculation of agreement.