Table 3.
Healthcare resources utilization at 28 days according to admission NT‐proBNP
| Variable | Low NT‐proBNP a | Borderline NT‐proBNP | High NT‐proBNP | |||
|---|---|---|---|---|---|---|
| (N = 417) | P value | (N = 141) | P value | (N = 121) | P value | |
| ICU admission | ||||||
| Events, N (%) | 111 (26.6) | 39 (27.7) | 38 (31.4) | |||
| OR (95%CI) b | 1.00 | Ref. | 1.28 (0.71–2.30) | 0.41 | 1.37 (0.67–2.81) | 0.39 |
| Mechanical ventilation | ||||||
| Events, N (%) | 92 (22.1) | 38 (27.0) | 33 (27.3) | |||
| OR (95%CI) | 1.00 | Ref. | 1.64 (0.90–2.99) | 0.10 | 1.58 (0.76–3.30) | 0.22 |
| Hospital‐free days | ||||||
| Days, mean (SD) | 15.9 (9.0) | 12.6 (9.8) | 10.7 (10.7) | |||
| RR (95%CI) | 1.00 | Ref. | 0.83 (0.65–1.07) | 0.15 | 0.65 (0.45–0.94) | 0.02 |
| ICU‐free days | ||||||
| Days, mean (SD) | 23.3 (9.0) | 19.4 (12.2) | 15.6 (13.5) | |||
| RR (95%CI) | 1.00 | Ref. | 0.87 (0.71–1.06) | 0.16 | 0.58 (0.41–0.83) | 0.003 |
| Ventilator‐free days | ||||||
| Days, mean (SD) | 23.9 (8.7) | 19.7 (12.0) | 15.9 (13.5) | |||
| RR (95%CI) | 1.00 | Ref. | 0.88 (0.72–1.08) | 0.23 | 0.61 (0.43–0.87) | 0.006 |
a
Categories of NT‐proBNP defined as in Table 1 .
b
All estimates have been adjusted for age, sex, race, history of hypertension, coronary artery disease, and chronic kidney disease, days from symptom onset, systolic blood pressure, temperature, creatinine, d‐dimer, troponin T, alanine aminotransferase, procalcitonin, and QTc on presentation.
CI, confidence interval; OR, odds ratio; RR, rate ratio; SD, standard deviation.