Table 2.
Univariable and multivariable Cox regression model for intra‐hospital mortality
| Univariable | Multivariable (N = 188) | ||||
|---|---|---|---|---|---|
| Level/units | HR (95% CI) | P value | HR (95% CI) | P value | |
| Troponin trend (vs. normal) | Elevated | 4.26 (2.00–9.07) | <0.001 | 2.61 (1.11–6.16) | 0.029 |
| Normal then elevated | 3.96 (1.32–11.92) | 0.014 | 3.78 (1.10–13.07) | 0.035 | |
| Elevated then normal | 4.32 (1.53–12.19) | 0.006 | 2.15 (0.70–6.56) | 0.180 | |
| Age | +5 years | 1.33 (1.17–1.52) | <0.001 | 1.25 (1.06–1.47) | 0.009 |
| Sex | M vs. F | 1.04 (0.55–1.97) | 0.907 | 1.54 (0.76–3.12) | 0.234 |
| Oxygen saturation | +5% | 0.80 (0.69–0.93) | 0.003 | 0.73 (0.61–0.88) | <0.001 |
| White body cell count | +1000 U/μL | 1.08 (1.02–1.13) | 0.005 | ||
| Lymphocytes count | +100 U/μL | 0.94 (0.89–1.00) | 0.055 | ||
| CRP | +10 mg/L | 1.04 (1.01–1.06) | 0.005 | 1.03 (1.00–1.05) | 0.075 |
| Lactate dehydrogenase | +1000 mg/dL | 1.10 (0.99–1.21) | 0.072 | ||
| ABG test lactate | +1 mmol/L | 1.18 (1.07–1.30) | 0.001 | ||
| PaO2/FiO2 | +50 mmHg/% | 0.85 (0.73–0.98) | 0.029 | ||
| Heart failure | Yes vs. no | 2.74 (1.47–5.11) | 0.002 | ||
| Coronary artery disease | Yes vs. no | 1.69 (0.92–3.10) | 0.093 | ||
| Atrial fibrillation | Yes vs. no | 1.94 (1.01–3.73) | 0.047 | ||
| Chronic obstructive pulmonary disease | Yes vs. no | 1.59 (0.71–3.54) | 0.259 | ||
| Diabetes | Yes vs. no | 1.86 (1.02–3.38) | 0.044 | ||
| Hypertension | Yes vs. no | 1.86 (1.01–3.42) | 0.045 | ||
| Chronic kidney disease | Yes vs. no | 3.56 (2.00–6.34) | <0.001 | 3.03 (1.51–6.08) | 0.002 |
| Prior ACEi/ARB therapy | Yes vs. no | 1.88 (1.04–3.39) | 0.035 | ||
Legend: ABG, arterial blood gas; ACEi, angiotensin‐converting enzyme inhibitor; ARB, angiotensin receptor blocker; CI, confidence interval; CRP, C‐reactive protein; FiO2, fraction of inspired oxygen; HR, hazard ratio; PaO2, oxygen partial pressure at arterial gas analysis; RBC, red blood cell.