TABLE 1.

Laboratory Investigations in Blood and Cerebrospinal Fluid (CSF) Done in All Three Cases

Blood investigation	Standardized investigation of CSF	Advanced virus investigation of CSF	Advanced antineuronal antibody investigation of serum and CSF
Cell count, kidney and liver function, thyroid function incl. Thyroid‐Antibodies, serum protein electrophoresis, HIV, Tuberculosis (TB)‐QuantiFERON blood test, vasculitis screen (ANA, Ena‐Screen, ANCA‐Screen, RF, anti‐ds DNA, C3c, C4, IgG, IgA, IgM)	CSF aspect, White blood cell count (/μl), Red blood cell count (/μl), Monocytes (%),Lymphocytes (%),Total Proteins (mg/l), Glucose (mg/dl), Lactate (mmol/l), Isoelectrofocusing, Syphilis, Lyme disease	DNA‐PCR of Herpes Simplex Virus, Varicella‐Zoster Virus, Cytomegaly and Epstein Barr Virus. Measles IgG, Rubella IgG, Herpes Simplex Virus 1/2 IgG, Varicella Zoster Virus IgG	GAD65, NMDA‐, and GABA‐B‐receptor, IgLON5, AMPA‐R subtype 2, DPPX, LGI1, CASPR2, Glycine‐receptor, mGluR5, mGluR1, Amphiphysin, CV2/CRMP5, Ma2/Ta, Hu, Ri, Yo, Zic4, Recoverin, Sox1, Titin, DNER/Tr