TABLE 2.
Univariate and multivariate analysis of factors associated with the 3‐month incomplete recovery from CD
| Univariate analysis | |||||
|---|---|---|---|---|---|
| Clinical, laboratory, and treatment‐related factors | n | OR | Lower 95% CI | Upper 95% CI | p |
| Hypertension | 134 | 0.47 | 0.20 | 1.10 | 0.081 |
| Hydroxychloroquine | 134 | 3.92 | 1.57 | 9.81 | 0.004 |
| Protease inhibitors | 134 | 3.58 | 1.28 | 10.04 | 0.015 |
| Steroids treatment | 134 | 0.52 | 0.21 | 1.34 | 0.176 |
| Age (+1 year) | 134 | 1.02 | 0.99 | 1.04 | 0.247 |
| Age (above median) | 134 | 1.29 | 0.58 | 2.84 | 0.531 |
| IL‐8 (above median) | 61 | 2.28 | 0.58 | 8.92 | 0.237 |
| Fibrinogen (above median) | 102 | 0.81 | 0.31 | 2.16 | 0.675 |
| Fibrinogen (above 400 mg/dl) | 102 | 0.49 | 0.15 | 1.60 | 0.239 |
| Neutrophil cell count (above median) | 128 | 0.53 | 0.22 | 1.26 | 0.152 |
| TNF‐alpha (above median) | 43 | 2.48 | 0.54 | 11.28 | 0.240 |
| TNF‐alpha (above 15 pg/ml) | 43 | 10.50 | 2.09 | 52.85 | 0.004 |
| Ferritin (above median) | 110 | 0.52 | 0.21 | 1.29 | 0.158 |
| Ferritin (above 150 μg/L) | 110 | 0.76 | 0.17 | 3.36 | 0.720 |
| Multivariate analysis | |||||
|---|---|---|---|---|---|
| Factors included in the logistic model | n | OR | Lower 95% CI | Upper 95% CI | p |
| Hypertension | 134 | 0.42 | 0.17 | 1.06 | 0.067 |
| Age (+1 year) | 134 | 1.03 | 1.00 | 1.06 | 0.052 |
| Steroids treatment | 134 | 0.33 | 0.12 | 0.92 | 0.033 |
| Protease inhibitors | 134 | 3.07 | 1.06 | 8.87 | 0.039 |
Note: The number of included values for each covariate considered into the model, limits of the 95% CI, and the p values are shown in the columns.
Abbreviations: CD, chemosensory dysfunction; CI, confidence interval; IL, interleukin; OR, odds ratio; TNF, tumor necrosis factor.