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. 2021 Aug 26;9:712190. doi: 10.3389/fpubh.2021.712190

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Copyright © 2021 Ding, Feng, Han, Zhou, Ji, Hao, Xue, Yin, Xu, Luo, Zhang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Kaplan-Meier analysis of clinical outcomes in critical COVID-19 patients. Kaplan–Meier curves between EF and non-EF patients for ARDS (A), complications (B), and survival (C) were analyzed. The Kaplan-Meier curves of EF and non-EF patients for ARDS (D), complications (E), and survival (F) after further dividing patients based on ΔT_max. T_max, maximum body temperature; ΔT_max, the difference between T_max in the last 3 days before end-hospitalization and T_max from symptom onset to the first clinic visit; COVID-19, coronavirus disease; EF, early fever, defined as the incidence of fever (T_max ≥ 37.3°C, measured using an ear thermometer) within 5 days of symptom onset. Complications included shock, disseminated intravascular coagulation, and multiple organ failure.