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. 2021 Aug 26;9:712190. doi: 10.3389/fpubh.2021.712190

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Copyright © 2021 Ding, Feng, Han, Zhou, Ji, Hao, Xue, Yin, Xu, Luo, Zhang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Risk factors for fatal COVID-19 outcome in the multivariate Cox proportional-hazards regression model. Shown in the figure are the hazard ratio (HR) and 95% confidence interval (95% CI) associated with the endpoint. Δ index(a), index(a) end-hospitalization - index(a) at the first clinic visit; T_max, maximum body temperature; ΔT_max, the difference between T_max in the last 3 days before end-hospitalization and T_max from symptom onset to the first clinic visit; COVID-19, coronavirus disease; EF, early fever, defined as the incidence of fever (T_max ≥ 37.3°C, measured using an ear thermometer) within 5 days of symptom onset. Chronic lung disease was defined as chronic obstructive pulmonary disease, asthma, or chronic bronchitis.