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. 2021 Aug 26;8:663920. doi: 10.3389/fmed.2021.663920

Table 3.

Sen, Spe, Acc, PPV, and NPV for serum NSE, CRP, and FC in discriminating between patients with CD and healthy people.

Sen (%) Spe (%) Acc (%) PPV (%) NPV (%)
NSE (in ng/mL cutoff 15.06) 48.98 82.88 67.41 70.59 65.94
CRP (in mg/L cutoff 7.93) 56.73 89.73 74.67 82.25 71.20
FC (in μg/g cutoff 752.40) 73.58 79.69 76.92 75.00 78.46
NSE+CRP 80.41 74.66 77.28 72.69 81.95

CD, Crohn's disease; NSE, neuron-specific enolase; CRP, C-reactive protein; FC, fecal calprotectin; Sen, sensitivity; Spe, specificity; Acc, accuracy; PPV, positive predictive value; NPV, negative predictive value.