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. 2021 Aug 26;15:734860. doi: 10.3389/fnins.2021.734860

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Copyright © 2021 Qiang, Wei, Chen and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic showing type 1, type 2, and type 3 MNV. (A) Type 1 MNV is an ingrowth of vessels originating from the choriocapillaris into the sub-RPE space. (B) Type 2 MNV is the proliferation of new vessels arising from the choroid into the subretinal space. (C) Type 3 MNV is a downgrowth of vessels from the retinal vascular plexus toward the outer retina. GCL, ganglion cell layer; IPL, inner plexiform layer; INL, inner nuclear layer; OPL, outer plexiform layer; ONL, outer nuclear layer; RPE, retinal pigment epithelium; MNV, macular neovascularization.