Fig. 4.

Transplantation of YZWJs513 hiPSC-NS/PCs promotes motor functional recovery after SCI in immunodeficient mice. (a) The motor function of each mouse was evaluated weekly after injury using the Basso Mouse Scale by two investigators who were blinded to the treatment of experimental mice. Sensitivity analyses with mixed-effects models for repeated measures revealed a significant difference at day 49. Data represent the means ± SEM (n = 10 for the control group and n = 8 for the transplantation group. ∗p < 0.05) (b) Treadmill gait analyses using the DigiGait System was performed at the sixth week after transplantation. Stride length was significantly longer in the transplantation group than in the control group. Data represent the means ± SEM (n = 10 for the control group and n = 8 for the transplantation group. ∗∗p < 0.01).