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ERRα is associated with PGC1α in hiPSC-CMs. (A–B) PGC-1α depletion by siRNA inhibited the expression of ERRα detected by qPCR (A) and Western blot analysis (B). Compared with negative control siRNA (Si-NC) group, ∗∗P < 0.01. (C) Co-IP experiments confirmed that PGC-1α interacts with ERRα in hiPSC-CMs. Immunoprecipition of PGC-1α was followed by immunoblotting using the indicated antibodies.
