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Causes of death of CML patients by front-line TKI treatment.
| Causes of death | First-line treatment | Total (N = 73) | ||||
|---|---|---|---|---|---|---|
| Imatinib (N = 56) | 2GTKI (N = 17) | |||||
| N | % | N | % | N | % | |
| CML-related | 11 | 19.6 | 10 | 58.8 | 21 | 28.8 |
| Other causes: | 45 | 80.4 | 7 | 41.2 | 52 | 71.2 |
| cardiac | 11 | 19.6 | 1 | 5.9 | 12 | 16.4 |
| neoplasia | 11 | 19.6 | 3 | 17.6 | 14 | 19.2 |
| lung | 3 | 5.4 | 0 | 0.0 | 3 | 4.1 |
| infections | 1 | 1.8 | 0 | 0.0 | 1 | 1.4 |
| neurologic | 5 | 8.9 | 0 | 0.0 | 5 | 6.8 |
| gastroenteric | 3 | 5.4 | 2 | 11.8 | 5 | 6.8 |
| other/unknown | 10 | 17.9 | 1 | 5.9 | 11 | 15.1 |
