Table 1.
Overview of BcR IG sequencing results.
| Family member | Stereotyped subset | IGHV gene | HCDR3 | IGLV/IGKV gene | LCDR3 |
|---|---|---|---|---|---|
| 1A | – | V1-3 | CARGVRFLEFLLYGDDAFDIW | IGKV1-33 IGK1-9 |
CQQYDNLPPALATVCQQVNSYPRITF |
| 1B | – | V4-34 V3-15 |
CARSLVVPAAYGPNSWFDSW CATGGHCGGACYSPYFDYW |
IGLV2-18 | CSLYTGTKTIF |
| 1C | – | V3-7 | CAKHDNTGDFHLDNW | IGKV1-16 IGLV2-11 |
CQQYNSYPALTF CCSYAGSHTYVF |
| 1D | – | V1-8 V2-5 V3-15 |
CARHPSRRCSGDFCSTGNWFDPW CLGHWVRGIMTPFDYW CNYYVMDVW |
IGKV3-20 IGLV2-14 |
CQQYGSSPNTF CSSYTSSNTLVF |
| 2A | – | V4-31 | CARLLAGLHYYYYYAMDVW | IGKV1-33 | CQQYDNLPPYTF |
| 2B | – | V4-34 | CARERRDSNYGSGIFYYYYGMDVW | IGKV4-1 | CQQYYSTPRTF |
| 3A | IGLV3-21R110 | V1-46 | CARAWSSAWKYYFDY | IGLV3-21 | CQVWDSGSDHPWVF |
| 3B | IGLV3-21R110/#169 | V3-48 | CARDGVGAPY | IGLV3-21 | CQVWDSGTDHPWVF |
| 3C | IGLV3-21R110/#2 | V3-21 | CARDQNGMDV | IGLV3-21 | CQVWDSSSDHPWVF |
| 3D | IGLV3-21R110 | V3-48 | CARDGGPCGDCYQ | IGLV3-21 | CLVWDSGSDHPYVF |