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Estimates of the log hazard ratio (HR) for mutation gene and penetrance at 70 years under different family designs with family size n = 150. The standard error of the estimates are indicated in brackets.
| Penetrance at 70 years | Penetrance at 70 years | ||
|---|---|---|---|
| Design | Log HR | in men (%) | in women (%) |
| CLI+ (High) | 1.84 (0.13) | 97.12 (0.95) | 75.63 (4.34) |
| POP+ (Med) | 0.95 (0.21) | 62.08 (5.62) | 25.08 (5.23) |
| POP (Low) | 0.46 (0.52) | 35.92 (13.73) | 14.17 (7.86) |
