Figure 1: IRC-assessed change in tumour volume from baseline.

(A) Patients with EZH2^mut follicular lymphoma. (B) Patients with EZH2^WT follicular lymphoma. Tumour responses were not estimable, missing, or unknown in five patients in the EZH2^WT cohort. Tumour volume was calculated as the sum of the product of perpendicular diameters according to the 2007 International Working Group criteria for non-Hodgkin lymphoma.²¹ Dashed red lines represent thresholds for progressive disease (≥50% increase in tumour volume) and partial response (≥50% reduction in tumour volume). The shaded area represents tumour volume changes that correspond to stable disease (<50% increase or decrease in tumour volume). IRC=independent radiology committee.