Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Aug 26;9:666422. doi: 10.3389/fcell.2021.666422

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Xie, Yao, Hu, Cai, Zhao, Yuan, Wu and Tang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

High-mobility group A1 (HMGA1) modulated the expression and phosphorylation of FOXO1. (A) The protein level of FOXO1 in heart tissue after AAV9-HMGA1 and ISO injection (n = 6). (B) The protein level of FOXO1 in CFs after HMGA1 siRNA and TGFβ1 treatment (n = 6). (C) The mRNA level of FOXO1 in heart tissue (left) and CFs (right) in each group (n = 6). (D) Luciferase reporter results in CFs with HMGA1 overexpression or HMGA1 silencing. *p < 0.05.