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. 2021 Aug 26;12:693071. doi: 10.3389/fgene.2021.693071

FIGURE 1.

FIGURE 1

The 9 “synthetic” and the 20 “analytic” hallmarks of aging as originally proposed in López-Otín et al. (2013). The wheel in the original figure proposes only 9 hallmarks of aging, but the text distinguishes more. The present article is based on the detailed hallmarks, which are represented here as an extension of the wheel.