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. 2021 Aug 26;12:718621. doi: 10.3389/fimmu.2021.718621

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Copyright © 2021 Chandrasekaran, Funk, Kleber, Paulos, Shanmugam and Waller

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Improving ACT Therapy with PI3K-δ and PI3K-γ Inhibition. Five distinct timepoints during ACT manufacturing are identified wherein intervention with PI3K-δ/-γ inhibitors may improve manufactured product quality and clinical outcomes.