Table 2.

Summary of Ki-67 Measurement Experiments Performed or Included in the Study^a

Hotspot Selector	Manual Counting	Analysis Platform
DIA pathologist	Observer 3 Observer 1	QuantCenter HALO
Observer 1	Observer 1
Observer 2	Observer 2	HALO

^aEach row indicates the hotspot selector and the methods of counting each of the selected hotspots were subjected to. The digital image analysis (DIA) pathologist study hotspots and observer 2 chosen hotspots were counted by both DIA platforms. Observer 1 counts on observer 1–chosen hotspots were performed as part of clinical reporting of each case.